switch calibration presets for different monitor setups

hi, i have a general question about the usage of soundID reference presets. 
iam about to configure my editing room with two sets of monitors:
1) a LCR midfield setup and 2) an LR nearfield setup - i would like to swich between both setups (so they wont play at the same time). what would be the most straight forward approach to achieve that? use one 5.1 calibration(adding L and R as LS and RS to the L C R configuration) and simply change/swicth RME totalmix output settings (via presets/snapshots)? Or make 2 different calibration settings and switch between them along with with my RME totalmix presets? 

Any tipp is pretty much appreciated. best, j